目的 观察具有药物过敏史人群视网膜脉络膜同步血管造影的不良反应发生率及处理。
方法 使用海德堡眼底血管造影仪对350例具有药物过敏史的患者进行同步造影，按体重同时注射荧光素钠和吲哚菁绿2种造影剂，观察记录不良反应的情况，分析不良反应率与既往药物过敏史的关系。
结果 350例药物过敏史患者造影有25例发生不良反应，发生率约为7.14％。其发生率与正常人群使用荧光素钠和吲哚菁绿同步造影报道的不良反应率5.20％是相似，其不良反应多为轻中度，主要为恶心、呕吐、头晕等。
结论 药物过敏史患者与正常人群使用荧光素钠和吲哚菁绿同步血管造影的不良反应相似，提示对具有药物过敏史人群进行同步血管造影是安全的。仔细观察药物过敏史患者不良反应，及时处理是非常重要的。
关键词  荧光素钠 吲哚菁绿 药物过敏 副作用 处理
Objective to determine the incidence rate and processing of the adverse reactions during retina and choroid angiography in drug allergy patients.
Methods 350 drug allergy patients were performed with Heidelberg Retinal and Choroid Angiography. Fluorescein Sodium and Indocyanine green were given according to the body weight and adverse reactions during angiography were observed. Objective the incidence rate for adverse reactions about drug allergy patients.
Results Adverse reactions were observed in 25 of 350(7.14%) cases .The incidence rate of the healthy population were observed in 5.20%. so results is similar to. the majority is at a mild to moderate degree. Nausea, sneezing, vomiting or pruritus. 
Conclusion retina and choroid angiography in drug allergy patients is a safe examination for the above patients. The incidence rate of adverse reaction due to retina and choroid angiography in these drug allergy patients is similar to that in the healthy population. Observing the drug allergy patients closely and timely processing is important to these special patients.
Key words  Sodium fluorescein   Indocyanine green    Drug allergy   Adverse reaction processing